Altman has long proposed the concept of humans merging with AI to form a new kind of life. In his 2017 blog post “The Merge,” Altman wrote “we can either be the biological bootloader for digital intelligence and then fade into an evolutionary tree branch, or we can figure out what a successful merge looks like.”
In December, 2025, Wired reported that Altman has already begun to build that dystopian cyborg future. His new venture, Merge Labs, is working to build brain-computer interfaces that will bring his predicted “merge” to life.
While he works to merge human and machine, Altman is also working to artificially extend human life, gene-edit babies, and build the “network state” infrastructure where democratic oversight of his experiments and endeavors is a distant memory.
Altman provided the entire $180 million seed round for Retro Biosciences, a startup focused on reversing biological aging. The company pursues heterochronic parabiosis (stitching circulatory systems of old and young mice together so the older animals receive “youthful” blood factors) and partial cellular reprogramming using what are known as modified Yamanaka factors. Retro works exclusively with OpenAI’s first biology-specialized model, ChatGPT-4b, which re-engineered the Yamanaka proteins to make cellular reprogramming roughly 50 times more efficient than human scientists had previously achieved.
Genetic Enhancement and Designer Babies
In early 2026 Altman and his husband invested in Preventative, a San Francisco startup developing CRISPR-style embryo editing to “eliminate hereditary diseases” and produce more resilient children. Although the company publicly emphasizes disease prevention, embryo selection or editing for traits such as IQ or height is an obvious next step once the technology works. Germline editing for reproduction is banned in the United States and most developed countries, so Preventative is scouting out jurisdictions including the United Arab Emirates that may be more permissive.
For-Profit Governance and Escape from Democracy
Altman is an investor in Próspera, a for-profit autonomous “startup city”/special economic zone on an island in Honduras operating under its own private legal and regulatory framework. The project markets itself as “building the future of human governance: privately run and for-profit,” with voluntary association and entrepreneurial innovation as its principles. Critics call it neocolonial corporate monarchy: wealthy CEOs writing rules for a poor country, low-tax deregulated enclaves with little accountability. When a subcontractor fell to his death from an unfinished tower at night, the company handled compensation internally under its own labor rules; no independent public investigation occurred. Próspera already hosts longevity clinics, reversible gene-therapy platforms, “human brain uploading” research, and a dedicated Longevity District. Peter Thiel and Marc Andreessen are also investors.